Massively enlarged spleen
Lymphoma
A 20 year old man presented with acute abdominal symptoms and was found to have a greatly enlarged spleen.
![[intact spleen.]](spleencap1.jpg)
The resected spleen is massively enlarged, and a tumor mass is visible through the capsule.
![[intact spleen.]](spleencap2.jpg)
The 1320 gram (nearly 3 pound) spleen was 230 mm long, and the tumor within it measured 180 mm (7 inches) in greatest dimension.
![[slab of spleen.]](spleenslab4.jpg)
A slice through the spleen shows a large well demarcated tumor which on frozen section appeared to be a lymphoma. (Flow studies at Vanderbilt showed a monotypic B cell large lymphocyte population that expressed monotypic kappa and coexpresses CD10, compatible with a follicular origin.) Large areas of necrosis are present in the tumor. Adjacent apparently normal spleen is visible on the viewer's left.
![[ct scan of spleen.]](spleenct12.jpg)
Spiral CT scan shows a 7 mm cut, with the greatly enlarged spleen (on the viewer's right), showing the less radiodense tumor mass with the somewhat denser adjacent normal spleen. IVP contrast medium provides enhancement.
Dr. Richmond's personal Web site map.
E-mail Bob Richmond
December 20th, 2000